Peroxisomes: key to cell performance and health
The Marie Curie Initial Training Network PERFUME (PERoxisome Formation, Function, Metabolism) is an interdisciplinary and intersectoral initial stage training network (ITN) at the interface of medicine, plant and fungal biology, devoted to understanding the principles of peroxisome biology.
Peroxisomes are ubiquitous organelles that are essential in man. Yet, the importance of the organelles is strongly underestimated. This is evident from the recent identification of several novel crucial functions, for instance related to resistance towards various stress conditions. Due to earlier considerable technical challenges the atlas of peroxisome functions is still far from complete. Further understanding of the significance of the intact organelle for cell performance demands directed analyses, which require the combined expertise from different disciplines and sectors that cut across historically separated fields.